CUI: Advanced Imaging of Matter
Cluster of ExcellenceCUI: Advanced
Imaging of Matter
Imaging of Matter
High-ranking funding for Dr. Henning TidowResearch into new antibiotics in the Heisenberg Programme
13 December 2022
Photo: Mathias Baustian
Chemist Henning Tidow analyzes membrane-bound proteins. They are important targets for novel drugs, among others.
Dr. Henning Tidow has been accepted into the Heisenberg Programme of the German Research Foundation (DFG). He will conduct research from 1 March 2023 as part of a Heisenberg position in the Department of Chemistry at Universität Hamburg. From 2014 until 2022 he led a research group as a junior professor at the Cluster of Excellence “CUI: Advanced Imaging of matter”.
Henning Tidow's research is strongly interdisciplinary and encompasses biochemistry as well as structural biology and applied physics. The focus is on the study of membrane-bound proteins. "Integral membrane proteins, shortly IMPs, transport substrates and signals across biological membranes and are an important class of drug targets," explains the researcher.
Within his Heisenberg project “Structural and dynamic studies of biomedically important integral membrane proteins”, Henning Tidow will study different classes of IMPs such as iron or lipid transporters with the long-term goal to develop for example novel drugs, specifically antibiotics. To this end, he will establish a new group at HARBOR, the Hamburg Advanced Research Centre for Bioorganic Chemistry” on the Bahrenfeld campus. Using integrative time-resolved structural biology, the researchers will investigate the structure as well as conformational changes of IMPs in a lipidic environment. Tidow will also continue to conduct research at the cluster "CUI: Advanced Imaging of Matter".
The program, named after the Nobel Prize winner for physics Werner Heisenberg, is the DFG's highest-ranking instrument for promoting young scientists. It is aimed at outstanding scientists who meet all the requirements for appointment to a long-term professorship. The five-year funding is designed to enable them to prepare for a senior academic role while continuing their research work.
